braincell.channel module#

Calcium Channels#

CaN_IS2008

Inoue & Strowbridge 2008 Ca-activated nonselective cation current.

CaL_IS2008

Inoue & Strowbridge 2008 L-type calcium current.

CaT_HM1992

Huguenard & McCormick 1992 low-threshold T-type calcium current.

CaT_HP1992

Huguenard & Prince 1992 T-type calcium current for reticular nucleus.

CaHT_HM1992

Depolarized-shift variant of the Huguenard & McCormick 1992 T current.

CaHT_Re1993

Reuveni 1993 high-threshold calcium current.

CaHVA_MA2020_GoC

Golgi cell high-voltage-activated calcium current.

CaHVA_MA2020_GrC

Granule cell high-voltage-activated calcium current.

CaHVA_SU2015_DCN

HVA calcium current of the DCN model (Sudhakar 2015).

CaLVA_SU2015_DCN

GHK-drive LVA calcium current of the DCN model (Sudhakar 2015).

CaL_SU2015_DCN

Ohmic-drive LVA calcium current of the DCN model (Sudhakar 2015).

Ca_ZH2019_IO

Somatic calcium current of the inferior-olive model (Zhang 2019).

Cav1p2_MA2020_GoC

Golgi cell Cav1.2 L-type calcium current with Ca inactivation.

Cav1p2_MA2025_BC

Cav1.2 L-type calcium current, basket-cell parameterisation.

Cav1p3_MA2020_GoC

Golgi cell Cav1.3 L-type calcium current with Ca inactivation.

Cav1p3_MA2025_BC

Cav1.3 L-type calcium current, basket-cell parameterisation.

Cav2p1_MA2024_PC

Purkinje cell Cav2.1 P-type calcium current, GHK drive.

Cav2p1_MA2024_PC_Frozen

Purkinje cell Cav2.1 with the GHK drive frozen for autodiff.

Cav2p1_MA2025_BC

Basket cell Cav2.1 P-type calcium current with GHK drive.

Cav2p1_RI2021_SC

Stellate cell Cav2.1 P-type calcium current with GHK drive.

Cav2p3_MA2020_GoC

Golgi cell Cav2.3 R-type, medium-threshold calcium current.

Cav3p1_MA2020_GoC

Golgi cell Cav3.1 low-threshold calcium current with GHK drive.

Cav3p1_MA2024_PC

Purkinje cell Cav3.1 low-threshold calcium current, GHK drive.

Cav3p1_MA2024_PC_Frozen

Purkinje cell Cav3.1 with the GHK drive frozen for autodiff.

Cav3p1Test_PC24

Cav3.1 test variant with the GHK drive replaced by a constant.

Cav3p2_MA2024_PC

Purkinje cell Cav3.2 low-threshold T-type calcium current.

Cav3p2_MA2025_BC

Basket cell Cav3.2 low-threshold T-type calcium current.

Cav3p2_RI2021_SC

Stellate cell Cav3.2 low-threshold T-type calcium current.

Cav3p3_MA2024_PC

Purkinje cell Cav3.3 low-threshold calcium current, GHK drive.

Cav3p3_MA2024_PC_Frozen

Purkinje cell Cav3.3 with the GHK drive frozen for autodiff.

Cav3p3_RI2021_SC

Stellate cell Cav3.3 low-threshold calcium current, GHK drive.

Hyperpolarization-Activated Channels#

HCN_HM1992

Hyperpolarization-activated current of Huguenard & McCormick (1992).

HCN_SU2015_DCN

H-current imported for the deep cerebellar nucleus (DCN) model.

HCN_ZH2019_IO

Inferior olive somatic h-current, imported from HCN_ZH19_IO.mod.

HCN1_MA2020_GoC

HCN1 fast/slow h-current imported for the Golgi cell model.

HCN1_MA2024_PC

HCN1 h-current imported for the human Purkinje cell model.

HCN1_MA2025_BC

HCN1 h-current imported for the cerebellar basket cell model.

HCN1_RI2021_SC

HCN1 h-current imported for the cerebellar stellate cell model.

HCN2_MA2020_GoC

HCN2 fast/slow h-current imported for the Golgi cell model.

Leakage Channels#

LeakageChannel

Base class for leakage channel dynamics.

IL

The leakage channel current.

Potassium Channels#

K_HH1952

Hodgkin-Huxley 1952 delayed-rectifier potassium current.

K_TM1991

Traub and Miles 1991 delayed-rectifier potassium current.

K_Leak

Potassium leak current.

K_Kv_test

Scratch Kv fixture built on the generic vtrap rate form.

KDR_Ba2002

Bazhenov 2002 delayed-rectifier potassium current.

Kdr_ZH2019_IO

Delayed rectifier of the inferior-olive model (Zhang 2019).

KA1_HM1992

Huguenard & McCormick 1992 A-type potassium current (IA1).

KA2_HM1992

Huguenard & McCormick 1992 A-type potassium current (IA2).

KK2A_HM1992

Huguenard & McCormick 1992 slow potassium current (IK2a).

KK2B_HM1992

Huguenard & McCormick 1992 slow potassium current (IK2b).

KNI_Ya1989

Yamada 1989 slow non-inactivating potassium current.

KM_MA2020_GoC

M-type potassium current of the Golgi cell model.

KM_MA2020_GrC

M-type potassium current of the granule cell model.

KM_RI2021_SC

M-type potassium current of the stellate cell model.

Kir2p3_MA2020_GrC

Kir2.3 inward-rectifier current of the granule cell model.

Kir2p3_MA2024_PC

Kir2.3 inward-rectifier current of the Purkinje cell model.

Kir2p3_MA2025_BC

Kir2.3 inward-rectifier current of the basket cell model.

Kir2p3_RI2021_SC

Kir2.3 inward-rectifier current of the stellate cell model.

Kv1p1_MA2020_GoC

Kv1.1 low-threshold potassium current of the Golgi cell model.

Kv1p1_MA2020_GrC

Kv1.1 low-threshold potassium current of the granule model.

Kv1p1_MA2024_PC

Kv1.1 low-threshold potassium current of the Purkinje model.

Kv1p1_MA2025_BC

Kv1.1 low-threshold potassium current of the basket cell model.

Kv1p1_RI2021_SC

Kv1.1 low-threshold potassium current of the stellate model.

Kv1p5_MA2020_GrC

Granule-cell Kv1.5 channel with two current owners.

Kv1p5_MA2024_PC

Kv1.5 ultrarapid delayed-rectifier current (IKur), K path only.

Kv2p2_0010_MA2020_GrC

Kv2.2 delayed-rectifier current of the granule cell model.

Kv3p3_MA2024_PC

Kv3.3 high-threshold potassium current of the Purkinje model.

Kv3p4_MA2020_GoC

Fast TEA-sensitive potassium current of the Golgi cell model.

Kv3p4_MA2020_GrC

Fast TEA-sensitive potassium current of the granule cell model.

Kv3p4_MA2024_PC

Fast TEA-sensitive potassium current of the Purkinje cell model.

Kv3p4_MA2025_BC

Fast TEA-sensitive potassium current of the basket cell model.

Kv3p4_RI2021_SC

Fast TEA-sensitive potassium current of the stellate cell model.

Kv4p3_MA2020_GoC

A-type transient potassium current of the Golgi cell model.

Kv4p3_MA2020_GrC

A-type transient potassium current of the granule cell model.

Kv4p3_MA2024_PC

A-type transient potassium current of the Purkinje cell model.

Kv4p3_MA2025_BC

A-type transient potassium current of the basket cell model.

Kv4p3_RI2021_SC

A-type transient potassium current of the stellate cell model.

fKdr_SU2015_DCN

Fast delayed rectifier of the DCN model (Sudhakar 2015).

sKdr_SU2015_DCN

Slow delayed rectifier of the DCN model (Sudhakar 2015).

Potassium-Calcium Channels#

AHP_De1994

Calcium-activated after-hyperpolarization current.

SK_SU2015_DCN

Small-conductance calcium-activated potassium current, DCN.

Kca1p1_MA2020_GoC

Kca1.1 (BK/mslo) Ca- and voltage-activated K current, Golgi cell.

Kca1p1_MA2020_GrC

Kca1.1 Ca- and voltage-activated K current, granule-cell variant.

Kca1p1_MA2024_PC

Kca1.1 Ca- and voltage-activated K current, Purkinje-cell variant.

Kca1p1_MA2025_BC

Kca1.1 Ca- and voltage-activated K current, basket-cell variant.

Kca1p1_RI2021_SC

Kca1.1 Ca- and voltage-activated K current, stellate-cell variant.

Kca2p2_MA2020_GoC

Kca2.2 (SK2) calcium-activated K current, Golgi cell.

Kca2p2_MA2020_GrC

Kca2.2 calcium-activated K current, granule-cell parameterisation.

Kca2p2_MA2024_PC

Kca2.2 calcium-activated K current, Purkinje-cell parameterisation.

Kca2p2_MA2025_BC

Kca2.2 calcium-activated K current, basket-cell parameterisation.

Kca2p2_RI2021_SC

Kca2.2 calcium-activated K current, stellate-cell parameterisation.

Kca3p1_MA2020_GoC

Kca3.1 (IK) calcium-activated K current, Golgi cell.

Kca3p1_MA2024_PC

Kca3.1 calcium-activated K current, Purkinje-cell parameterisation.

Kca3p1_MA2025_BC

Kca3.1 calcium-activated K current, basket-cell parameterisation.

Sodium Channels#

Na_HH1952

Hodgkin-Huxley 1952 sodium current with \(p^3 q\) HH gating.

Na_TM1991

Traub and Miles 1991 sodium current with \(p^3 q\) HH gating.

Na_Ba2002

Bazhenov 2002 sodium current with \(p^3 q\) HH gating.

Na_ZH2019_IO

Inferior olive somatic sodium current, Schweighofer kinetics.

NaF_SU2015_DCN

Fast sodium current of the deep cerebellar nuclei model.

NaP_SU2015_DCN

Persistent sodium current of the deep cerebellar nuclei model.

NaFHF_MA2020_GrC

Resurgent Nav sodium current with slow block, granule-cell model.

Nav_MA2020_GrC

Resurgent Nav sodium current, granule-cell parameterisation.

Nav1p1_MA2025_BC

Non-resurgent Nav1.1 sodium current, basket-cell parameterisation.

Nav1p1_RI2021_SC

Non-resurgent Nav1.1 sodium current, stellate-cell parameterisation.

Nav1p6_MA2020_GoC

Resurgent Nav1.6 sodium current, Golgi-cell parameterisation.

Nav1p6_MA2024_PC

Resurgent Nav1.6 sodium current, Purkinje-cell parameterisation.

Nav1p6_MA2025_BC

Resurgent Nav1.6 sodium current, basket-cell parameterisation.

Nav1p6_RI2021_SC

Resurgent Nav1.6 sodium current, stellate-cell parameterisation.