CdpStC_RI2021_SC

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CdpStC_RI2021_SC#

class braincell.ion.CdpStC_RI2021_SC(size, temp=Quantity(298.15, 'K'), Nannuli=10.9495, cainull=Quantity(4.5e-05, 'mM'), mginull=Quantity(0.59, 'mM'), Buffnull1=Quantity(0., 'mM'), rf1=Quantity(0.0134329, '1 / (mM * ms)'), rf2=Quantity(0.0397469, 'kHz'), Buffnull2=Quantity(60.9091, 'mM'), rf3=Quantity(0.1435, '1 / (mM * ms)'), rf4=Quantity(0.0014, 'kHz'), BTCnull=Quantity(0., 'mM'), b1=Quantity(5.33, '1 / (mM * ms)'), b2=Quantity(0.08, 'kHz'), DMNPEnull=Quantity(0., 'mM'), c1=Quantity(5.63, '1 / (mM * ms)'), c2=Quantity(0.000107, 'kHz'), PVnull=Quantity(0.08, 'mM'), m1=Quantity(107., '1 / (mM * ms)'), m2=Quantity(0.00095, 'kHz'), p1=Quantity(0.8, '1 / (mM * ms)'), p2=Quantity(0.025, 'kHz'), kpmp1=Quantity(0.003, '1 / (mM * ms)'), kpmp2=Quantity(1.75e-05, 'kHz'), kpmp3=Quantity(7.255e-05, 'kHz'), TotalPump=Quantity(1.e-09, 'mol / cm^2'), Co=None, Ci_initializer=None, species_initializers=None, solver='backward_euler', substeps=1, name=None, **channels)#

Calcium pool for the stellate cell, no calmodulin buffering.

The same pump/non-CaM-buffer/parvalbumin kinetic network documented in CdpStC_NoCAM_MA2020_GoC, reused unchanged for the cerebellar stellate cell model of Rizza et al. (2021) [4].

Parameters:

See also

CdpStC_NoCAM_MA2020_GoC

The base class; full network, parameters and equilibrium initializers are documented there.

CdpStC_MA2025_BC

Same kinetics, basket-cell model citation.

Notes

Ported from SC/ion/CdpStC_RI21_SC.mod, whose header names Anwar, Hong & De Schutter [1] as the reference for the mechanism, credits the extended buffer parameters to Schmidt et al. (2003) [2], and records the pump rate as tuned to data from Maeda et al. (1999) [3]. This class does not override __init__: the reaction network, the source and the conservation relation are all inherited unchanged from CdpStC_NoCAM_MA2020_GoC. Only the register_ion key and this docstring’s model citation differ. The source .mod file also reads an extracellular calcium variable cao that its kinetic equations never use; BrainCell drops that unused read rather than reproducing it.

References

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