Cav3p1_MA2024_PC#
- class braincell.channel.Cav3p1_MA2024_PC(size, g_max=Quantity(0.00025, 'cm / s'), V_sh=Quantity(0., 'mV'), temp=Quantity(295.15, 'K'), q10=3.0, temp_ref=Quantity(310.15, 'K'), name=None)#
Purkinje cell Cav3.1 low-threshold calcium current, GHK drive.
The same \(p^2 q\) Cav3.1 kinetics and GHK current law documented in
Cav3p1_MA2020_GoC, reused unchanged for the human Purkinje cell model of (Masoli et al., 2024) [3]. The kinetics remain the fit to (Iftinca et al., 2006) [1] published in (Anwar, Hong & De Schutter, 2012) [2].- Parameters:
size (
int|Sequence[int] |integer|Sequence[integer]) – Channel state shape.g_max (
Array|ndarray|bool|number|bool|int|float|complex|Quantity|Callable) – Calcium permeability entering the GHK flux (the mod file’spcabar), default2.5e-4 cm/s. Inherited fromCav3p1_MA2020_GoC.V_sh (
Array|ndarray|bool|number|bool|int|float|complex|Quantity|Callable) – Accepted but read by no method of this class (seeCav3p1_MA2020_GoCNotes). Default0.0 mV. Inherited fromCav3p1_MA2020_GoC.temp (
Array|ndarray|bool|number|bool|int|float|complex|Quantity) – Absolute temperature entering both theqtfactor and the GHK flux, default 22 degrees Celsius. Inherited fromCav3p1_MA2020_GoC.q10 (
Array|ndarray|bool|number|bool|int|float|complex|Quantity|Callable) – Q10 factor forqt, default3.0. Inherited fromCav3p1_MA2020_GoC.temp_ref (
Array|ndarray|bool|number|bool|int|float|complex|Quantity) – Reference temperature forqt, default 37 degrees Celsius. Inherited fromCav3p1_MA2020_GoC.
See also
Cav3p1_MA2020_GoCThe base class; the full equation set, the GHK helper’s constants, the tau-embedded temperature handling and the header corrections are documented there.
Cav3p1_MA2024_PC_FrozenPurkinje-cell variant with the GHK term’s voltage dependence removed from the autodiff graph. It is not a subclass of this class (see its Notes).
Cav3p1Test_PC24Anonymous test variant of the same mechanism with the GHK drive replaced by a direct conductance-density current law.
Notes
Ported from
PC/channel/Cav3p1_MA24_PC.mod. An earlier revision of this docstring named the source fileCav3p1_MA24_PC.mod, which does not exist; the shipped file uses the two-digit year code, and that is corrected here. That file is identical toGoC/channel/Cav3p1_MA20_GoC.modexcept for itsSUFFIXline and a droppedINDEPENDENTstatement, neither of which affects the kinetics. Accordingly this class overrides nothing: the constructor, the gate declarations, the named Boltzmann/tau parameter block and thecurrentmethod are all inherited fromCav3p1_MA2020_GoC. Only theregister_channelkey and this docstring’s model citation differ.The
MA2024import-deviations tables list noTABLEremoval, no integration-method substitution and no rate-refresh relocation forCav3p1.References